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The material state of centrosomes: lattice, liquid, or gel?

Woodruff, J.B. Current Opinion in Structural Biology, 2021. Review.

Regulated changes in material properties underlie centrosome disassembly during mitotic exit

Mittasch, M.*, Tran, V.M.*, Rios, M.U., Fritsch, A.W., Enos, S.J., Ferreira Gomes, B., Bond, A., Kreysing, M., Woodruff, J.B. Journal of Cell Biology, 2020.

*Co-first authors.

Soluble tubulin is significantly enriched at centrosomes

Baumgart J, Kirchner M, Redemann S, Bond A, Woodruff J, Verbavatz JM, Jülicher F, Müller-Reichert T, Hyman AA, Brugués J. Journal of Cell Biology, 2019.

FlexiBAC: a versatile, open-source baculovirus vector system for protein expression, secretion, and proteolytic processing

Lemaitre, R., Bogdanova, A., Borgonovo B., Woodruff, J.B., Drechsel, D.N. BMC Biotechnology, 2019.

Assembly of mitotic structures through phase separation

Woodruff, J.B. Journal of Molecular Biology, 2018. Review.

Organization and function of non-dynamic biomolecular condensates

Woodruff, J.B., Hyman A.A., Boke, E. Trends in Biochemical Sciences, 2018. Review.

Phosphatase PP2A and microtubule-mediated pulling forces disassemble centrosomes during mitotic exit

Enos, S.J., Dressler, M., Ferreira Gomes, B., Hyman, A.A, Woodruff, J.BBiology Open, 2018.

The centrosome is a selective condensate that nucleates microtubules by concentrating tubulin

Woodruff, J.B., Ferreira Gomes, B., Widlund, P.O., Mahamid, J., Honigmann, A. & Hyman, A. A. Cell, 2017. [Video Abstract]

Polo-like kinase phosphorylation determines C. elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation

Wueseke, O., Zwicker, D., Schwager, A., Wong, Y.L., Oegema, K., Jülicher, F., Hyman, A.A., Woodruff, J.B. Biology Open, 2016. [Video Abstract]

Regulated assembly of a supramolecular centrosome scaffold in vitro

Woodruff, J.B.*, Wueseke, O.*, Viscardi, V., Mahamid, J., Ochoa, S.D., Bunkenborg, J., Widlund, P.O., Pozniakovsky, A., Zanin, E., Bahmanyar, S., Zinke, A., Hong, S.H., Decker, M., Baumeister, W., Andersen, J.S., Oegema, K., Hyman, A.A.  Science, 2015 *Co-first authors. 

Pericentriolar material structure and dynamics

Woodruff, J.B., Wueseke, O., Hyman, A.A. Philosophical Transactions of the Royal Society B, 2014. Review.

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