The material state of centrosomes: lattice, liquid, or gel?

Woodruff, J.B. Current Opinion in Structural Biology, 2021. Review.

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Regulated changes in material properties underlie centrosome disassembly during mitotic exit

Mittasch, M.*, Tran, V.M.*, Rios, M.U., Fritsch, A.W., Enos, S.J., Ferreira Gomes, B., Bond, A., Kreysing, M., Woodruff, J.B. Journal of Cell Biology, 2020.

*Co-first authors.

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Soluble tubulin is significantly enriched at centrosomes

Baumgart J, Kirchner M, Redemann S, Bond A, Woodruff J, Verbavatz JM, Jülicher F, Müller-Reichert T, Hyman AA, Brugués J. Journal of Cell Biology, 2019.

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FlexiBAC: a versatile, open-source baculovirus vector system for protein expression, secretion, and proteolytic processing

Lemaitre, R., Bogdanova, A., Borgonovo B., Woodruff, J.B., Drechsel, D.N. BMC Biotechnology, 2019.

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Assembly of mitotic structures through phase separation

Woodruff, J.B. Journal of Molecular Biology, 2018. Review.

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Organization and function of non-dynamic biomolecular condensates

Woodruff, J.B., Hyman A.A., Boke, E. Trends in Biochemical Sciences, 2018. Review.

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Phosphatase PP2A and microtubule-mediated pulling forces disassemble centrosomes during mitotic exit

Enos, S.J., Dressler, M., Ferreira Gomes, B., Hyman, A.A, Woodruff, J.B. Biology Open, 2018.

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The centrosome is a selective condensate that nucleates microtubules by concentrating tubulin

Woodruff, J.B., Ferreira Gomes, B., Widlund, P.O., Mahamid, J., Honigmann, A. & Hyman, A. A. Cell, 2017. [Video Abstract]

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Polo-like kinase phosphorylation determines C. elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation

Wueseke, O., Zwicker, D., Schwager, A., Wong, Y.L., Oegema, K., Jülicher, F., Hyman, A.A., Woodruff, J.B. Biology Open, 2016. [Video Abstract]

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Regulated assembly of a supramolecular centrosome scaffold in vitro

Woodruff, J.B.*, Wueseke, O.*, Viscardi, V., Mahamid, J., Ochoa, S.D., Bunkenborg, J., Widlund, P.O., Pozniakovsky, A., Zanin, E., Bahmanyar, S., Zinke, A., Hong, S.H., Decker, M., Baumeister, W., Andersen, J.S., Oegema, K., Hyman, A.A.  Science, 2015 *Co-first authors. 

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Pericentriolar material structure and dynamics

Woodruff, J.B., Wueseke, O., Hyman, A.A. Philosophical Transactions of the Royal Society B, 2014. Review.

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