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    WOODRUFF LAB

    UT Southwestern Medical Center

    Department of Cell Biology and Biophysics

    © 2018 Jeff Woodruff

    jeffrey.woodruff*at*utsouthwestern.edu

    NL 6.110A, 6000 Harry Hines Blvd. 

    Dallas, TX

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    Synthetic embryology

    RESEARCH

     

    LAB NEWS

     

    • 7/13/2019. Manolo is selected for the Pharmacological Sciences training grant. Congrats!

    • 4/2/2019. We present FlexiBAC, our baculovirus  expression system for difficult proteins.  Read it at BMC Biotechnology.

    • 2/28/2019. Our first graduate student joins! Welcome Manolo!

    • 2/4/2019. The Nikon spinning disk confocal is live and ready for experiments.

    • 1/7/2019. The lab welcomes its second rotation student Charis Springhower.

    • 12/1/2018. Vanna visits Dresden for round two of destroying centrosomes using FLUCS.

    FEATURED MOVIE

    With a FLUCS microscope, we use light to induce flows within a living embryo. This allows us to apply tunable force against centrosomes to study their material properties. In the movie, FLUCS deforms and ruptures a centrosome (white).

     

    Credit: Vanna Tran and Matthaus Mittasch

    Eggs can survive in a dormant state for many years. They then reawaken and form a complex organism after fertilization. How does this happen? We use synthetic biology, live-cell imaging, and nano-scale rheology to understand how eggs guard themselves against ageing and faulty cell division.

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