Synthetic embryology

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FEATURED MOVIE

We use light to induce flows within a living embryo. This allows us to apply tunable force against centrosomes to study their material properties. In the movie, FLUCS deforms and ruptures a centrosome (green) during anaphase. DNA is magenta.

Mittasch, Tran et al., 2020 Journal of Cell Biology

Eggs can survive in a dormant state for many years. They then reawaken and form a complex organism after fertilization. How does this happen? We use synthetic biology, live-cell imaging, and nano-scale rheology to understand how eggs guard themselves against ageing and faulty cell division.

© 2020 Jeff Woodruff

jeffrey.woodruff*at*utsouthwestern.edu

NL 6.110A, 6000 Harry Hines Blvd. 

Dallas, TX

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