© 2018 Jeff Woodruff

jeffrey.woodruff*at*utsouthwestern.edu

NL 6.110A, 6000 Harry Hines Blvd. 

Dallas, TX

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Synthetic embryology

RESEARCH

 

LAB NEWS

 

  • 2/27/2020. Jeff speaks in the Rising Stars session at Chromopalooza! at the Vienna BioCenter. Thanks to the student organizers for a great event!

  • 2/16/2020. The lab welcomes its newest grad student, Priyankaa.

  • 2/10/2020. Our FLUCS paper is now online at the Journal of Cell Biology.  A great collaboration with the Kreysing Lab!

  • 12/10/2019. Jeff and Dan Jarosz co-chair the session, "Phase transitions: from phenomenon to function" at the ASCB conference in Washington, D.C.

  • 11/11/2019. Manolo is granted a travel award for the ASCB conference.

FEATURED MOVIE

We use light to induce flows within a living embryo. This allows us to apply tunable force against centrosomes to study their material properties. In the movie, FLUCS deforms and ruptures a centrosome (green) during anaphase. DNA is magenta.

Mittasch, Tran et al., 2020 Journal of Cell Biology

Eggs can survive in a dormant state for many years. They then reawaken and form a complex organism after fertilization. How does this happen? We use synthetic biology, live-cell imaging, and nano-scale rheology to understand how eggs guard themselves against ageing and faulty cell division.