© 2018 Jeff Woodruff


NL 6.110A, 6000 Harry Hines Blvd. 

Dallas, TX

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Synthetic embryology





  • 12/10/2019. Jeff and Dan Jarosz co-chair the session, "Phase transitions: from phenomenon to function" at the ASCB conference in Washington, D.C.

  • 12/6/2019. Our FLUCS paper uncovering the functional material properties of centrosomes is now on BioRxiv.

  • 11/11/2019. Manolo is granted a travel award for the ASCB conference.

  • 7/13/2019. Manolo is selected for the Pharmacological Sciences training grant. Congrats!

  • 4/2/2019. We present FlexiBAC, our baculovirus  expression system for difficult proteins.  Read it at BMC Biotechnology.


With a FLUCS microscope, we use light to induce flows within a living embryo. This allows us to apply tunable force against centrosomes to study their material properties. In the movie, FLUCS deforms and ruptures a centrosome (white).


Credit: Vanna Tran and Matthaus Mittasch

Eggs can survive in a dormant state for many years. They then reawaken and form a complex organism after fertilization. How does this happen? We use synthetic biology, live-cell imaging, and nano-scale rheology to understand how eggs guard themselves against ageing and faulty cell division.